OBESITY AND OSTEOARTHRITIS: A BIOMECHANICAL AND GLOBAL HEALTH EVALUATION OF TOTAL KNEE ARTHROPLASTY PATIENTS AND HEALTHY CONTROLS

dc.contributor.advisor Stickley, Cris
dc.contributor.author Linsley, Laura Mary
dc.contributor.department Kinesiology and Rehabilitation Science
dc.date.accessioned 2021-09-30T18:13:32Z
dc.date.available 2021-09-30T18:13:32Z
dc.date.issued 2021
dc.description.degree Ph.D.
dc.identifier.uri http://hdl.handle.net/10125/76404
dc.subject Biomechanics
dc.subject Kinesiology
dc.subject Biomechanics
dc.subject Gait
dc.subject KOOS JR.
dc.subject Osteoarthritis
dc.subject PROMIS
dc.subject Total Knee Arthroplasty
dc.title OBESITY AND OSTEOARTHRITIS: A BIOMECHANICAL AND GLOBAL HEALTH EVALUATION OF TOTAL KNEE ARTHROPLASTY PATIENTS AND HEALTHY CONTROLS
dc.type Thesis
dcterms.abstract Three-dimensional biomechanical gait analysis is a clinical tool to measure patient function prior to and following total knee arthroplasty (TKA). Patient-reported outcome (PRO) measures are psychometric questionnaires that also measure patient function prior to and following TKA. Different insight is gained from each of these measurement tools, the biomechanical data measures local factors, the PRO measures global factors, the current study utilized the Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS JR.) and the Patient-Reported Outcomes Measurement Information System (PROMIS) Global Physical Health (GPH) and Global Mental Health (GMH). Body mass index (BMI) is another important measurement tool that provides insight into patient health, BMI is a local factor as well. How do TKA patients recover over time in terms of their BMI, biomechanical gait, and PRO measures? Results of this dissertation suggest that biomechanically, there were significant group differences between healthy controls and TKA patients. Comparing healthy controls to TKA patients also revealed that there were baseline differences related to BMI, and group differences over time related to BMI that significantly affected the biomechanical gait outcomes. Furthermore, PRO measures for all TKA patients improved over time. The KOOS JR. and PROMIS GPH significantly improved at each timepoint, there was a lag effect for the PROMIS GMH. Patients with a higher BMI had worse baseline KOOS JR., GPH, and GMH scores. For the GPH and GMH the effect of BMI was non-significant over time. The KOOS JR. scores significantly interacted with BMI, over time at six months and one year, suggesting that heavier patients improve their scores more over time.
dcterms.extent 204 pages
dcterms.language en
dcterms.publisher University of Hawai'i at Manoa
dcterms.rights All UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.
dcterms.type Text
local.identifier.alturi http://dissertations.umi.com/hawii:11126
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