Symbiont-induced changes in host gene expression: The squid-Vibrio symbiosis
Symbiont-induced changes in host gene expression: The squid-Vibrio symbiosis
dc.contributor.advisor | McFall-Ngai, Margaret | |
dc.contributor.author | Kimbell, Jennifer Loraine | |
dc.contributor.department | Biomedical Sciences (Cellular & Molecular Biology) | |
dc.date.accessioned | 2008-04-17T18:45:52Z | |
dc.date.available | 2008-04-17T18:45:52Z | |
dc.date.graduated | 2003-12 | |
dc.date.issued | 2003-12 | |
dc.description.abstract | All animals exist in lifelong relations with a complement of bacteria. Because of the ubiquity of these symbioses as well as the derived biomedical applications, the study of both beneficial and pathogenic host-microbe associations has long been established. The monospecific light organ association between the Hawaiian sepiolid squid Euprymnascolopes and the marine luminous bacterium Vibrio fischeri has been used as a experimental model for the study of the most common type of animal-bacterial interaction, i.e., the association of coevolved Gram-negative bacteria with the extracellular apical surfaces of polarized epithelia. A fundamental step for understanding the mechanisms of host-symbiont associations lies in defining the genetic components involved; specifically defining changes in host gene expression. The studies presented in this dissertation identify and characterize V. fischeri-induced changes in host gene expression at both the transcript and protein level. | |
dc.identifier.citation | Kimbell, Jennifer Loraine (2003) Symbiont-induced changes in host gene expression: The squid-Vibrio symbiosis. Ph.D. dissertation, University of Hawai'i, United States -- Hawaii. | |
dc.identifier.uri | http://hdl.handle.net/10125/1259 | |
dc.language.iso | en-US | |
dc.publisher | University of Hawaii at Manoa | |
dc.relation | Theses for the degree of Doctor of Philosophy (University of Hawaii at Manoa). Biomedical Sciences (Cell & Molecular Biology); no. 4398 | |
dc.rights | All UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner. | |
dc.rights.uri | https://scholarspace.manoa.hawaii.edu/handle/10125/865 | |
dc.subject | Host gene expression | |
dc.subject | Symbiosis | |
dc.subject | Vibrio fischeri | |
dc.subject | Euprymna scolopes | |
dc.subject | Light organs | |
dc.subject | Cellular biology | |
dc.subject | Molecular biology | |
dc.title | Symbiont-induced changes in host gene expression: The squid-Vibrio symbiosis | |
dc.type | Thesis | |
dc.type.dcmi | Text | |
local.identifier.callnumber | AC1 .H3 no. 4398 | |
local.thesis.degreelevel | PhD |
Files
Original bundle
1 - 2 of 2
No Thumbnail Available
- Name:
- uhm_phd_4398_r.pdf
- Size:
- 7.83 MB
- Format:
- Adobe Portable Document Format
- Description:
- Version for non-UH users. Copying/Printing is not permitted
No Thumbnail Available
- Name:
- uhm_phd_4398_uh.pdf
- Size:
- 7.83 MB
- Format:
- Adobe Portable Document Format
- Description:
- Version for UH users
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 1.71 KB
- Format:
- Item-specific license agreed upon to submission
- Description: