Effects of the Perfusion Pressure on the Tolerance of an Isolated Rat Heart to Total Coronary Flow Cessation
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2014-01-15
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University of Hawaii at Manoa
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Using various modifications of the Langendorff technique, it has been fairly well established that an increase in coronary perfusion pressure results in a linear increase in the coronary flow rate; an elevated systolic pressure; a higher oxygen consumption; no appreciable change in heart rate; a slight decline in diastolic pressure; an in the KCl-arrested guinea pig heart, a lengthening of the hyocardial sarcomeres.
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5 pages
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