Policy implications for prevention of highly pathogenic avian influenza subtype H5N1 in conjunction with risk factors in the Red River Delta, Vietnam

Abstract

The challenge is to develop the vaccination program that is more successful in containing and preventing the Highly Pathogenic Avian Influenza subtype H5N1 from recurrence in the Red River Delta, Vietnam and reducing vaccination costs. This study addresses the tradeoff between the current policy which implements an annual two-round vaccination for the entire geographical area of the Delta and an alternative policy which involves more frequent vaccination in higher probability areas for the disease occurrence within the Delta. The ex-ante analysis framework is used to identify the location of higher probability areas for the alternative policy and evaluate the accuracy of the analysis. The efficacy and cost analysis of vaccination programs are then implemented for the tradeoff between the current and the alternative policies. The ex-ante analysis suggests that the focus areas for the alternative vaccination program include 1137 communes, corresponding to 50.6% of total communes in the Delta and mostly located in the coastal areas to the east and south of Hanoi. The efficacy and cost analyses suggests that the alternative policy would be more successful in reducing the rate of disease occurrence and the costs of vaccination as compared to the current policy.