Effects of Simulated Preparations of Plants used in Nigerian Traditional Medicine on Candida spp. Associated with Vaginal Candidiasis

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dc.contributor.author Ogunshe, Adenike A.O.
dc.contributor.author Lawal, Oladipupo A.
dc.contributor.author Iheakanwa, Chinedum I.
dc.date.accessioned 2009-09-17T22:42:18Z
dc.date.available 2009-09-17T22:42:18Z
dc.date.issued 2008
dc.description research
dc.description.abstract Some Nigerian medicinal plants are popular among traditional producers of phytotherapies in the treatment of sexually related infections. For this study we used modified agar disk, agar spot and agar well-diffusion methods, preparations of simulated crude aqueous and ethanolic extracts of 11 traditionally used medicinal plants for in vitro antimicrobial activities against seventy five strains of Candida species associated with Candida vaginitis and 37 vaginal Lactobacillus species. Candida pseudotropicalis (Castell.) Basgal were minimally inhibited by the plant extracts, while the rate of inhibition of other Candida strains by the ethanolic extracts of the plants were, Ageratum conyzoides L. (44.4 - 66.7%), Anthocleista djalonensis A. Chev. (57.1 - 66.7%), Senna alata (L.) Roxb. (44.4 - 75.0%) Ficus exasperata Vahl. (44.4 - 62.5%), Gliricidia sepium Kunth ex Steud. (64.3%-75.0%) Chromolaena odorata (L.) R.M. King & H. Rob.(57.1%-62.5%) and Rauwolfia vomitoria Afzel. (62.5%). Apart from Aspilia africana (Pers.) C.D. Adams (24.3%) and Ageratum conyzoides L. (35.1%), very low in vitro inhibitory activities of between 5.4% and 16.2% were produced by the medicinal plants against the vaginal Lactobacillus species indicating their ethnophytotherapeutic safety.
dc.identifier.citation Ogunshe AAO. Lawal OA, Iheakanwa CI. 2008. Effects of simulated preparations of plants used in Nigerian traditional medicine on Candida spp. associated with vaginal candidiasis. Ethnobotany Research and Applications 6:373-383.
dc.identifier.issn 1547-3465
dc.identifier.uri http://hdl.handle.net/10125/12493
dc.language.iso en-US
dc.publisher University of Hawaii at Manoa
dc.subject Nigeria
dc.subject Africa
dc.subject traditional medicine
dc.subject medicinal plants
dc.subject Candida
dc.title Effects of Simulated Preparations of Plants used in Nigerian Traditional Medicine on Candida spp. Associated with Vaginal Candidiasis
dc.type Article
dc.type.dcmi Text
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2008 - Volume 6 : Ethnobotany Research and Applications