Family Income, Parental Education and Brain Structure in Children and Adolescents

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dc.contributor.authorNoble, Kimberly G.
dc.contributor.authorHouston, Suzanne M.
dc.contributor.authorBrito, Natalie H.
dc.contributor.authorBartsch, Hauke
dc.contributor.authorKan, Eric
dc.contributor.authorKuperman, Joshua
dc.contributor.authorAkshoomoff, Natacha
dc.contributor.authorAmaral, David G.
dc.contributor.authorBloss, Cinnamon S.
dc.contributor.authorLibiger, Ondrej
dc.contributor.authorSchork, Nicolas J.
dc.contributor.authorMurray, Sarah S.
dc.contributor.authorCasey, B.J.
dc.contributor.authorChang, Linda
dc.contributor.authorErnst, Thomas M.
dc.contributor.authorFrazier, Jean A.
dc.contributor.authorGruen, Jeffrey R.
dc.contributor.authorKennedy, David N.
dc.contributor.authorVan Zijl, Peter
dc.contributor.authorMostofsky, Stewart
dc.contributor.authorKaufmann, Walter E.
dc.contributor.authorKenet, Tal
dc.contributor.authorDale, Anders M.
dc.contributor.authorJernigan, Terry L.
dc.contributor.authorSowell, Elizabeth R.
dc.contributor.authorPediatric Imaging, Neurocognition, and Genetics Study
dc.date.accessioned2016-04-29T22:27:15Z
dc.date.available2016-04-29T22:27:15Z
dc.date.issued2015-05
dc.description.abstractSocioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. Here, we investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1099 typically developing individuals between 3 and 20 years. Income was logarithmically associated with brain surface area. Specifically, among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data indicate that income relates most strongly to brain structure among the most disadvantaged children. Potential implications are discussed.
dc.format.extent23
dc.identifier.doi10.1038/nn.3983
dc.identifier.urihttp://hdl.handle.net/10125/40210
dc.language.isoen-US
dc.publisherNature
dc.relation.urihttp://www.nature.com/neuro/journal/v18/n5/full/nn.3983.html
dc.relation.urihttp://www.ncbi.nlm.nih.gov/pubmed/25821911
dc.titleFamily Income, Parental Education and Brain Structure in Children and Adolescents
dc.typeArticle
dc.type.dcmiText

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