Family Income, Parental Education and Brain Structure in Children and Adolescents

dc.contributor.author Noble, Kimberly G.
dc.contributor.author Houston, Suzanne M.
dc.contributor.author Brito, Natalie H.
dc.contributor.author Bartsch, Hauke
dc.contributor.author Kan, Eric
dc.contributor.author Kuperman, Joshua
dc.contributor.author Akshoomoff, Natacha
dc.contributor.author Amaral, David G.
dc.contributor.author Bloss, Cinnamon S.
dc.contributor.author Libiger, Ondrej
dc.contributor.author Schork, Nicolas J.
dc.contributor.author Murray, Sarah S.
dc.contributor.author Casey, B.J.
dc.contributor.author Chang, Linda
dc.contributor.author Ernst, Thomas M.
dc.contributor.author Frazier, Jean A.
dc.contributor.author Gruen, Jeffrey R.
dc.contributor.author Kennedy, David N.
dc.contributor.author Van Zijl, Peter
dc.contributor.author Mostofsky, Stewart
dc.contributor.author Kaufmann, Walter E.
dc.contributor.author Kenet, Tal
dc.contributor.author Dale, Anders M.
dc.contributor.author Jernigan, Terry L.
dc.contributor.author Sowell, Elizabeth R.
dc.contributor.author Pediatric Imaging, Neurocognition, and Genetics Study
dc.date.accessioned 2016-04-29T22:27:15Z
dc.date.available 2016-04-29T22:27:15Z
dc.date.issued 2015-05
dc.description.abstract Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. Here, we investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1099 typically developing individuals between 3 and 20 years. Income was logarithmically associated with brain surface area. Specifically, among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data indicate that income relates most strongly to brain structure among the most disadvantaged children. Potential implications are discussed. en_US
dc.format.extent 23 en_US
dc.identifier.doi 10.1038/nn.3983
dc.identifier.uri http://hdl.handle.net/10125/40210
dc.language.iso en-US en_US
dc.publisher Nature en_US
dc.relation.uri http://www.nature.com/neuro/journal/v18/n5/full/nn.3983.html en_US
dc.relation.uri http://www.ncbi.nlm.nih.gov/pubmed/25821911 en_US
dc.title Family Income, Parental Education and Brain Structure in Children and Adolescents en_US
dc.type Article en_US
dc.type.dcmi Text en_US
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