Lower Body Muscle Function in Frail and Non-Frail People Living with HIV: A Pilot Study

Simple item page
dc.contributor.advisorKimura, Iris
dc.contributor.authorBoyle, Rachel
dc.contributor.departmentEducation
dc.date.accessioned2020-07-07T19:12:04Z
dc.date.available2020-07-07T19:12:04Z
dc.date.issued2020
dc.description.degreeD.Ed.
dc.identifier.urihttp://hdl.handle.net/10125/68978
dc.subjectKinesiology
dc.subjectFraity
dc.subjectHuman Immunodeficiency Virus
dc.subjectLower Body Function
dc.subjectStrength
dc.titleLower Body Muscle Function in Frail and Non-Frail People Living with HIV: A Pilot Study
dc.typeThesis
dcterms.abstractAge-related accelerated physical declines occur in people living with HIV (PLWH) a decade earlier than HIV-uninfected (HIV-) individuals resulting in complications that lead to physical dysfunction and loss of independence. Fried’s Frailty Phenotype (FFP) is a common frailty assessment used to assess these multidimensional complications in PLWH, however lacks sufficient lower body muscle function measurements. The purpose of this study was to objectively assess lower body muscle function (LBMF) in FFP groups using the 30-second chair stand test (30CST) and the Manual Muscle Testing (MMT). Forty PLWH ≥50 years on antiretroviral therapy (ART), categorized into frailty groups (non-frail, pre-frail, frail), were assessed for and lower leg extension (LLE) strength. Average age was 60 (interquartile: 57-66), 95% were male, and 67.5% Caucasian. Both TLBF and body fat (BF) discriminated between (p<0.05) and among (p<0.01) frailty groups. LLE strength showed no differences between groups. Total lean body mass (LBM) and fat free mass (FFM) only discriminated between (p<0.05) non-frail and combined frailty groups (pre-frail + frail). BF significantly correlated (p<0.05) with pre-frail TLBF and frail LLE strength groups while lean LBM significantly correlated (p<0.05) only with pre-frail LLE strength. To our knowledge, this is the first study to assess 30 CST, MMT, and body composition in the presence of frailty in PLWH. Our findings indicate that 30 CST and body composition are measures that can be utilized in identifying declines in lower body muscle function in frail PLWH.
dcterms.extent88 pages
dcterms.languageeng
dcterms.publisherUniversity of Hawai'i at Manoa
dcterms.rightsAll UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.
dcterms.typeText
local.identifier.alturihttp://dissertations.umi.com/hawii:10578

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Boyle_hawii_0085A_10578.pdf
Size:
865.52 KB
Format:
Adobe Portable Document Format
Download

Collections

Ed.D. - Education