Photoprotection by Plant-derived Compounds

Date
2014-09-26
Authors
Shelton, Hannah
Contributor
Advisor
Williams, Philip
Department
Chemistry
Instructor
Depositor
Speaker
Researcher
Consultant
Interviewer
Journal Title
Journal ISSN
Volume Title
Publisher
University of Hawaii at Manoa
Volume
Number/Issue
Starting Page
Ending Page
Alternative Title
Abstract
Current topical sunscreens, although effective, may not be the safest way to prevent UVradiation based skin damage. Active petroleum-derived ingredients may be toxic, and may not be the most cost-effective solution for sunscreen production. The compounds responsible for protecting plants' cellular structures from UV radiation have the potential to be an effective alternative. This project sought to determine the worth of three plant-derived compounds – lycopene, genistein, and astaxanthin – as potential sunscreen ingredients. First, SPF and Boots Star System data from in vitro UV absorption spectra were collected. Second, each compound was exposed over UV-sensitive cyantoype emulsion, in lieu of human skin, in order to determine comparative in vivo properties. While not as effective as petroleum based ingredients, these compounds showed the potential to be safe sunscreen additives, or the primary active ingredients in low SPF lotions. Additionally, the use of cyanotype emulsion was effective at determining the level of UV light permitted through a solution. Although not perfect, it has proved to be a versatile and inexpensive replacement for human skin in this experiment.
Description
Keywords
Citation
Extent
i, 26 pages
Format
Geographic Location
Time Period
Related To
Rights
All UHM Honors Projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.
Rights Holder
Email libraryada-l@lists.hawaii.edu if you need this content in ADA-compliant format.