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Effects of Hawai`i-grown Coffee on Plasma Fructosamine and Antioxidant Capacity in Healthy Individuals
File under embargo until 2021-07-01
|Title:||Effects of Hawai`i-grown Coffee on Plasma Fructosamine and Antioxidant Capacity in Healthy Individuals|
|Contributors:||Nerurkar, Pratibha V. (advisor)|
Molecular Biosciences and Bioengineering (department)
show 2 moreFructosamine
|Publisher:||University of Hawai'i at Manoa|
|Abstract:||Hawai`i-grown coffee from Kauai (Yellow Catuai) and from Waialua (Kona Typica) contain bioactive compounds with properties that may modify type 2 diabetes risk. This pilot study aims to evaluate the antioxidant capacity and mineral and metal content of the coffees, and post-coffee consumption effects on plasma antioxidant capacity and fructosamine levels. In this randomized crossover study, 12 healthy adults consumed 24 oz of coffee per day for four weeks for each coffee intervention, which was separated by a one-week washout period. Data was collected at the end of the washout and intervention periods. Coffee brews were analyzed for mineral and metal content, as well as antioxidant capacity by oxygen radical absorbance (ORAC) assay. Plasma antioxidant capacity was measured at washout and after interventions using ORAC assay. Mineral analysis of coffee brews demonstrated no significant differences between the mineral components of each coffee. However, manganese content in a 24 oz cup of Waialua coffee was found to contribute up to 26% of the daily adequate intake. Metals were negligible, indicating low likelihood of metal toxicity. Based on coffee ORAC results, there are no significant changes in antioxidant capacity in Waialua coffee compared to Kauai coffee. Plasma fructosamine levels did not significantly change with coffee intervention and remained within normal limits. Plasma ORAC values were not different between washout and intervention with either coffee types. In conclusion, the Hawai`i-grown coffee cultivars had no detrimental effect on glucose metabolism and study participants did not demonstrate significant changes in plasma antioxidant capacity.|
|Description:||M.S. Thesis. Ph.D. Thesis. University of Hawaiʻi at Mānoa 2019|
|Rights:||All UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.|
|Appears in Collections:||
M.S. - Molecular Biosciences and Bioengineering|
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