Anton, EduardOesterreich, Thuy DuongFitte, ChristianTeuteberg, Frank2021-12-242021-12-242022-01-04978-0-9981331-5-7http://hdl.handle.net/10125/79817In this study, we examine the configurations of trust-enhancing factors that determine the intention to adopt conversational agents (CAs) for disease diagnosis. After identifying trust factors influencing the behavioral intent to adopt CAs based on the information systems acceptance research field, we assigned 201 participants to use the mobile Ada application and surveyed them about their experience. Ada is a medical diagnostic CA that combines patients’ symptoms with their medical history and provides diagnostic suggestions. The collected data was analyzed using a fuzzy set qualitative comparative analysis to capture the causal complexity of trust. We identified several configurations of trust-enhancing factors affecting the intention to adopt the CA. In particular, our results show that the adoption intentions are strongly determined by trust factors associated with the performance dimension. Furthermore, we derived two propositions for the development of CAs for healthcare purposes and elaborated implications for research and practice.10 pagesengAttribution-NonCommercial-NoDerivatives 4.0 InternationalIT Adoption, Diffusion, and Evaluation in Healthcareconversational agentsfsqcahealthcaretrusttext10.24251/HICSS.2022.481