The Barrious Oil Wrapping System (BOWS), A Dietary Supplement To Aid In The Treatment Of Obesity
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2004-12
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The Barrious Oil Wrapping System (BOWS), a commercial dietary supplement, was tested. Using in vitro titrimetric assays with olive oil (100 mg), BOWS caused a 50% decrease in pancreatic lipase activity between 50 and 75 mg. This is consistent with BOWS blocking the action of lipase by sequestering the oil out of solution. Juvenile rats fed 24% fat containing 10% BOWS diets weighed significantly less than rats fed control. Rats fed 10% fat with 5 or 10% BOWS had significantly less intraperitoneal fat than rats eating a 10% fat diet. Rats fed 20% fat with 15% BOWS diets gained significantly less weight than rats eating the control diet. BOWS was associated with decreased blood glucose levels suggesting that BOWS could playa role in managing type 2 diabetes. It was concluded that BOWS could be effective in weight loss programs that also include social support and/or satiety maximizing diets.
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Theses for the degree of Master of Science (University of Hawaii at Manoa). Molecular Biosciences and Bioengineering; no. 3917
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