A Critical Analysis of Dengue Fever in Hawaii
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2014-01-15
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University of Hawaii at Manoa
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WhileDengue fever has been present throughout the world for centuries, its potential impact as a public health crisis is still emerging.Dengue (DENV) is an arbovirus, of the genus Flavivirus, transmitted to humans by female Aedes mosquitoes. It has been suggested that the earliest account of dengue infection occurred in China dating back to 992 A.D. [ 1]. The first documented cases of dengue in the Pacific region occurred during the early 20th century. About the time of World War II, DENV outbreaks were present throughout Southeast Asia and spread to many islands in the Pacific, including Hawai'i. With the aid of globalization during this time,DENV could now be transported through infected people to other regions of the world in a matter of days, even hours. Due to the incubation period from the time of infection to clinical symptoms (from 3 to 14 days), individuals were not immediately aware that they were infected. Thus, worldwide travel provided a mechanism for rapid dissemination of the virus.DENV-1 phylogenie analysis has illustrated gene envelope relations, which help to illustrate their origins and spread patterns. My research has focused on the origins, vectors of transmission, and control of spread that were involved in the Hawaiian outbreaks of dengue fever. Based on historical evidence, information was compiled to recount past dengue outbreaks in Hawai'i through both an etic and ernie point of view.
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15 pages
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