Diversity in Digital Pill Systems: Differences in Perceptions and Attitudes Towards Use of a Digital Pill System for HIV Pre-Exposure Prophylaxis Among Men Who Have Sex With Men with Diverse Racial and Ethnic Identities

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dc.contributor.author Lee, Jasper
dc.contributor.author Albrechta, Hannah
dc.contributor.author Goodman, Georgia
dc.contributor.author De, Dikha
dc.contributor.author Takabatake, Koki
dc.contributor.author O’Cleirigh, Conall
dc.contributor.author Mayer, Kenneth
dc.contributor.author Fisher, Celia
dc.contributor.author Carnes, Chris
dc.contributor.author Chai, Peter R.
dc.date.accessioned 2022-12-27T19:06:13Z
dc.date.available 2022-12-27T19:06:13Z
dc.date.issued 2023-01-03
dc.description.abstract Nonadherence, particularly among men who have sex with men (MSM) with substance use disorders increases the risk of both HIV acquisition in those who are uninfected and the risk of disease progression and transmission in those with HIV. Measuring adherence to HIV pre-exposure chemoprophylaxis (PrEP) and antiretroviral therapy (ART), and responding to suboptimal adherence or changes in adherence behavior, remains a challenging public health problem. Despite the importance of accurate adherence measurement, there remains no gold standard for detecting medication ingestion events in HIV research. Technologies have been developed that indirectly infer ingestion events (e.g., via smart pill bottles) or directly measure adherence over periods of time (e.g., via drug concentration in plasma and red blood cells), yet such approaches fail to provide direct confirmation of ingestions and contextual information surrounding adherence and nonadherence. The use of a digital pill system (DPS) – a novel tool that leverages ingestible radiofrequency sensors to measure actual ingestion events – has the potential to advance adherence measurement in HIV research. In this study, we examined the willingness of MSM across racial and ethnic identities to operate a DPS in the context of PrEP adherence measurement and suggest potential future applications of this technology.
dc.format.extent 10
dc.identifier.doi 10.24251/HICSS.2023.361
dc.identifier.isbn 978-0-9981331-6-4
dc.identifier.uri https://hdl.handle.net/10125/102992
dc.language.iso eng
dc.relation.ispartof Proceedings of the 56th Hawaii International Conference on System Sciences
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject Health Behavior Change Support Systems
dc.subject digital pill systems
dc.subject hiv pre-exposure prophylaxis
dc.subject ingestible sensors
dc.subject medication adherence
dc.title Diversity in Digital Pill Systems: Differences in Perceptions and Attitudes Towards Use of a Digital Pill System for HIV Pre-Exposure Prophylaxis Among Men Who Have Sex With Men with Diverse Racial and Ethnic Identities
dc.type.dcmi text
prism.startingpage 2933
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