Please use this identifier to cite or link to this item: http://hdl.handle.net/10125/50240

Big Data and Parkinson’s Disease: Exploration, Analyses, and Data Challenges.

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Title: Big Data and Parkinson’s Disease: Exploration, Analyses, and Data Challenges.
Authors: SenthilarumugamVeilukandammal, Mahalakshmi
Nilakanta, Sree
Ganapathysubramanian, Baskar
Anantharam, Vellareddy
Kanthasamy, Anumantha
show 1 moreA Willette, Auriel
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Keywords: Big Data on Healthcare Application
Big Data, Data Challenges, Parkinson's, Sparse data, Visualization
Issue Date: 03 Jan 2018
Abstract: In healthcare, a tremendous amount of clinical and laboratory tests, imaging, prescription and medication data are being collected. Big data analytics on these data aim at early detection of disease which will help in developing preventive measures and in improving patient care. Parkinson disease is the second-most common neurodegenerative disorder in the United States. To find a cure for Parkinson's disease biological, clinical and behavioral data of different cohorts are collected, managed and propagated through Parkinson’s Progression Markers Initiative (PPMI). Applying big data technology to this data will lead to the identification of the potential biomarkers of Parkinson’s disease. Data collected in human clinical studies is imbalanced, heterogeneous, incongruent and sparse. This study focuses on the ways to overcome the challenges offered by PPMI data which is wide and gappy. This work leverages the initial discoveries made through descriptive studies of various attributes. The exploration of data led to identifying the significant attributes. We are further working to build a software suite that enables end to end analysis of Parkinson’s data (from cleaning and curating data, to imputation, to dimensionality reduction, to multivariate correlation and finally to identify potential biomarkers).
Pages/Duration: 6 pages
URI/DOI: http://hdl.handle.net/10125/50240
ISBN: 978-0-9981331-1-9
DOI: 10.24251/HICSS.2018.352
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
Appears in Collections:Big-Data on Healthcare Application


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