Please use this identifier to cite or link to this item: http://hdl.handle.net/10125/40210

Family Income, Parental Education and Brain Structure in Children and Adolescents

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Title:Family Income, Parental Education and Brain Structure in Children and Adolescents
Authors:Noble, Kimberly G.
Houston, Suzanne M.
Brito, Natalie H.
Bartsch, Hauke
Kan, Eric
show 21 moreKuperman, Joshua
Akshoomoff, Natacha
Amaral, David G.
Bloss, Cinnamon S.
Libiger, Ondrej
Schork, Nicolas J.
Murray, Sarah S.
Casey, B.J.
Chang, Linda
Ernst, Thomas M.
Frazier, Jean A.
Gruen, Jeffrey R.
Kennedy, David N.
Van Zijl, Peter
Mostofsky, Stewart
Kaufmann, Walter E.
Kenet, Tal
Dale, Anders M.
Jernigan, Terry L.
Sowell, Elizabeth R.
Pediatric Imaging, Neurocognition, and Genetics Study
show less
Date Issued:May 2015
Publisher:Nature
Relation:http://www.nature.com/neuro/journal/v18/n5/full/nn.3983.html
http://www.ncbi.nlm.nih.gov/pubmed/25821911
Abstract:Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. Here, we investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1099 typically developing individuals between 3 and 20 years. Income was logarithmically associated with brain surface area. Specifically, among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data indicate that income relates most strongly to brain structure among the most disadvantaged children. Potential implications are discussed.
Pages/Duration:23
URI/DOI:http://hdl.handle.net/10125/40210
DOI:10.1038/nn.3983
Appears in Collections: John A. Burns School of Medicine Faculty & Researcher Works


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