Please use this identifier to cite or link to this item:

Detection of Mutagens in the Areca Nut with Two Microbial Assays

File Size Format  
biology5002.PDF 581.4 kB Adobe PDF View/Open

Item Summary

Title:Detection of Mutagens in the Areca Nut with Two Microbial Assays
Authors:Yen, Catherine
Contributors:Biology (department)
Date Issued:15 Jan 2014
Publisher:University of Hawaii at Manoa
Abstract:The areca nut (Areca catechu Linn.) is commonlychewed in India and other eastern countries, and this practice has been associated with an increased incidence of oral cancer. Most known carcinogens are also mutagens, therefore it is probable that areca nuts contain a mutagen. A host-mediated and an in vitro microbial assay were used to screen the areca nut for mutagens. Neither the whole nut nor extracts of it showed any evidence of mutagenic activity. The urine of mice fed the areca likewise gave no indications of mutagenicity. It is possible that the nut does not contain a mutagen, or that a mutagen in the nut is not concentrated enough to detect with the assays used.
Pages/Duration:24 pages
Rights:All UHM Honors Projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.
Appears in Collections: Honors Projects for Biology

Please email if you need this content in ADA-compliant format.

Items in ScholarSpace are protected by copyright, with all rights reserved, unless otherwise indicated.