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Symbiont-induced changes in host gene expression: The squid-Vibrio symbiosis

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DC FieldValueLanguage
dc.contributor.advisorMcFall-Ngai, Margareten_US
dc.contributor.authorKimbell, Jennifer Loraineen_US
dc.date.accessioned2008-04-17T18:45:52Z-
dc.date.available2008-04-17T18:45:52Z-
dc.date.issued2003-12en_US
dc.identifier.citationKimbell, Jennifer Loraine (2003) Symbiont-induced changes in host gene expression: The squid-Vibrio symbiosis. Ph.D. dissertation, University of Hawai'i, United States -- Hawaii.en_US
dc.identifier.urihttp://hdl.handle.net/10125/1259-
dc.description.abstractAll animals exist in lifelong relations with a complement of bacteria. Because of the ubiquity of these symbioses as well as the derived biomedical applications, the study of both beneficial and pathogenic host-microbe associations has long been established. The monospecific light organ association between the Hawaiian sepiolid squid Euprymnascolopes and the marine luminous bacterium Vibrio fischeri has been used as a experimental model for the study of the most common type of animal-bacterial interaction, i.e., the association of coevolved Gram-negative bacteria with the extracellular apical surfaces of polarized epithelia. A fundamental step for understanding the mechanisms of host-symbiont associations lies in defining the genetic components involved; specifically defining changes in host gene expression. The studies presented in this dissertation identify and characterize V. fischeri-induced changes in host gene expression at both the transcript and protein level.en_US
dc.language.isoen-USen_US
dc.publisherUniversity of Hawaii at Manoaen_US
dc.relationTheses for the degree of Doctor of Philosophy (University of Hawaii at Manoa). Biomedical Sciences (Cell & Molecular Biology); no. 4398en_US
dc.rightsAll UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.en_US
dc.rights.urihttps://scholarspace.manoa.hawaii.edu/handle/10125/865en_US
dc.subjectHost gene expressionen_US
dc.subjectSymbiosisen_US
dc.subjectVibrio fischerien_US
dc.subjectEuprymna scolopesen_US
dc.subjectLight organsen_US
dc.subjectCellular biologyen_US
dc.subjectMolecular biologyen_US
dc.titleSymbiont-induced changes in host gene expression: The squid-Vibrio symbiosisen_US
dc.typeThesisen_US
dc.type.dcmiTexten_US
dc.contributor.departmentBiomedical Sciences (Cellular & Molecular Biology)en_US
dc.date.graduated2003-12en_US
local.identifier.callnumberAC1 .H3 no. 4398en_US
local.thesis.degreelevelPhDen_US
Appears in Collections:Ph.D. - Biomedical Sciences (Cell & Molecular Biology)


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