Item Description

Show full item record

Title: The biology of mammalian spermatozoa in the oviduct 
Author: Smith, Todd Timothy
Date: 1990
Abstract: The oviduct occupies a unique position in mammalian reproduction as the site of sperm transport, the final maturation of sperm and egg, fertilization, and the initial development of the embryo. This dissertation examines the factors that control the number, distribution and physiological state of spermatozoa in the oviduct. The golden hamster (Mesocricetus auratus) was used as the animal model. The following summarizes my findings. The uterotubal junction restricts the passage of homologous and heterologous spermatozoa into the oviduct, furthermore, sperm motility is essential for efficient passage. After mating, spermatozoa rapidly enter the oviductal isthmus where they are stored. When mating occurs shortly after the onset of estrus, spermatozoa are stored for at least 8 h until near the time of ovulation. When mating occurs during ovulation, spermatozoa are stored for a minimum of 3 h. Spermatozoa stored in the isthmus during the preovulatory period do not become fully capacitated until near the time of ovulation. When mating occurs during ovulation, spermatozoa require a minimum of 3 h in the isthmus to become fully capacitated. Although many thousands of spermatozoa are stored in the isthmus, only a relatively small percentage of these spermatozoa survive. The spermatozoa that do survive attach to the oviductal mucosa during storage. Later, due to physiological changes in the sperm head plasma membrane that accompany capacitation, a small number of these spermatozoa detach from the mucosa and ascend to the ampulla to fertilize the eggs.
Description: Typescript. Thesis (Ph. D.)--University of Hawaii at Manoa, 1990. Includes bibliographical references (leaves 97-104) Microfiche. ix, 109 leaves, bound ill. 29 cm
URI: http://hdl.handle.net/10125/9361
Rights: All UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.
Keywords: Mammals -- Spermatozoa, Oviduct

Item File(s)

Description Files Size Format View
Restricted for viewing only uhm_phd_9107052_r.pdf 3.036Mb PDF View/Open
For UH users only uhm_phd_9107052_uh.pdf 3.005Mb PDF View/Open

This item appears in the following Collection(s)

Search


Advanced Search

Browse

My Account

Statistics

About