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Browsing Ph.D. - Biomedical Sciences (Cell & Molecular Biology) by Subject "Molecular biology"

Now showing items 1-4 of 4

The LOX and LOXL2 amine oxidases in colon and esophageal cancer

Fong, Sheri Fumiko Tsuda (University of Hawaii at Manoa, 2003-12)

Several members of the lysyl oxidase family of copper-dependent amine oxidases have been implicated in tumor development. The Iysyl oxidase (LOX) and LOX-like 2 (LOXL2) genes have been mapped to chromosomal regions affected ...
N-myc oncogene expression in neuroblastoma is dependent on Sp1 and Sp3

Tuthill, Matthew Charles (University of Hawaii at Manoa, 2003-12)

Regulation of N-myc oncogene expression is an important determinant of the biological behavior of neuroblastoma. The N-myc promoter contains several potential binding sites for transcription factors of the Sp1 family. ...
Symbiont-induced changes in host gene expression: The squid-Vibrio symbiosis

Kimbell, Jennifer Loraine (University of Hawaii at Manoa, 2003-12)

All animals exist in lifelong relations with a complement of bacteria. Because of the ubiquity of these symbioses as well as the derived biomedical applications, the study of both beneficial and pathogenic host-microbe ...
The use of suppression subtractive hybridization in the identification of a novel gene encoding a protein containing a BTB-POZ domain in the Mediterranean fruit fly, Ceratitis capitata

Untalan, Pia Marie (University of Hawaii at Manoa, 2002-12)

Differential gene expression plays a key role in developmental pathways within an organism. Examples of such pathways include primary sex determination signaling and the formation of secondary sexual characteristics. This ...