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dc.contributor.advisor Nerurkar, Vivek R en_US
dc.contributor.author Isami, Fumiyuki en_US
dc.date.accessioned 2009-03-06T19:37:29Z en_US
dc.date.available 2009-03-06T19:37:29Z en_US
dc.date.issued 2003-12 en_US
dc.identifier.uri http://hdl.handle.net/10125/7035 en_US
dc.description viii, 69 leaves en_US
dc.description.abstract There is high prevalence of a methionine substitution at the tip of the V3 loop (MGPGQ) among HIV CRF_AE strains from Vietnam. The aim of this study was to identify other molecular markers or ""signature sequences"" for mapping the spread of HIV in Vietnam and in neighboring Southeast Asian countries. Analysis of the sequence diversity and grouping by molecular markers suggested that ET strain initially gained entry in CSW in southern Vietnam. Unique substitutions among ECM and EC- strains in southern Vietnam IDU and CSW suggested independent introduction and spread of HIV among these high-risk groups. Unique and identical amino acid substitutions found in ECV strains from IDU in northern Vietnam and southern China suggested cross-border travel of virus-infected IDU. en_US
dc.publisher University of Hawaii at Manoa en_US
dc.rights All UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner. en_US
dc.rights.uri https://scholarspace.manoa.hawaii.edu/handle/10125/870 en_US
dc.title Bioinformatic approach for tracking HIV-1 evolution in Vietnam and neighboring southeast Asian countries en_US
dc.type Thesis en_US
dc.type.dcmi Text en_US
dc.contributor.department Biomedical Sciences (Tropical Medicine - Cell, Mollecular, & Neuro Sciences) en_US
dc.description.degree MS en_US
dc.date.graduated 2003-12 en_US
local.identifier.callnumber Q111 .H3 no. 3832 en_US

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