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The Synthesis of a Retinal Analog and Its Visual Pigment Formation

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Title: The Synthesis of a Retinal Analog and Its Visual Pigment Formation
Authors: Tong, Dominic
Issue Date: 15 Jan 2014
Publisher: University of Hawaii at Manoa
Abstract: The present study involves the synthesis of a retinal analog and its visual pigment formation with opsin protein extracted from cattle retinas. In the course of working on such a project as this, it became increasingly evident that the visual system and the retinal-opsin complex, in particular, involves knowledge gleaned from both biology and chemistry. Part I contains the synthesis of the retinal analog and requires the use of existing methods in organic chemistry. Vision researchers are realizing mare and more everyday that they must draw on the resources of organic chemistry for the preparation of retinal and retinal derivatives. Part II consists of details on the visual pigment formation of the retinal analog synthesized in Part I. It must be stressed that this is a preliminary investigation and further work must be done in order to draw definite conclusions about the interaction of the retinal analog with the opsin protein.
Pages/Duration: iv, 144 pages
Rights: All UHM Honors Projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.
Appears in Collections:Honors Projects for Biology

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