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The Effects of C-Reactive Protein and Platelet-Activating Factor in Platelet Aggregation and in Superoxide Anion and Hydrogen Peroxide Formation

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Title: The Effects of C-Reactive Protein and Platelet-Activating Factor in Platelet Aggregation and in Superoxide Anion and Hydrogen Peroxide Formation
Authors: Iwamoto, Lynn
Issue Date: 15 Jan 2014
Publisher: University of Hawaii at Manoa
Abstract: The initial observation was made by Tillet and Francis in 1930 in patients in the acute phase of lobar pneumonia (3). In 1941, Abernethy and Avery designated the term CRP based on its binding to C-polysaccharide via phosphorylcholine residues, in the presence of calcium (4). Many other compounds, including nucleotides, nucieic acids, carbohydrates, and lipids, react with CRP by phosphorylcholine binding (2). Since its first discovery, CRP has been found in several mammals and other vertebrates (2) and at elevated levels during the acute episodes of a variety of diseases.
Pages/Duration: iv, 49 pages
URI/DOI: http://hdl.handle.net/10125/31939
Rights: All UHM Honors Projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.
Appears in Collections:Honors Projects for Biology



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