Browsing Office of Public Health Studies Faculty & Researcher Works by Author "Chai, Weiwen"

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  • Chai, Weiwen; Conroy, Shannon M; Maskarinec, Gertraud; Franke, Adrian A; Pagano, Ian S; Cooney, Robert V (2010-04)
    Elucidating potential pathways that micronutrients may reduce/promote chronic disease may contribute to our understanding of the underlying etiology of disease and their utility as markers of risk. In the current study, ...
  • Chai, Weiwen; Bostick, Roberd; Ahearn, Thomas; Franke, Adrian A.; Custer, Laurie J.; Cooney, Robert V. (Routledge, 2012-01)
    -Tocopherol (T) protects against DNA-damaging effects of nitrogen oxides, yet its physiologic regulation in vivo is unknown. Observational studies indicate inverse associations of 25[OH]-vitamin D with T and leptin. ...
  • Conroy, Shannon M; Chai, Weiwen; Lim, Unhee; Franke, Adrian A; Cooney, Robert V; Maskarinec, Gertraud (2011)
    Ethnic differences in adipose tissue distribution may contribute to different chronic disease risks across ethnic groups, and adipokines may mediate the risk. In a cross-sectional study, we examined ethnic differences in ...
  • Cooney, Robert V; Dai, Qi; Gao, Yu-Tang; Chow, Wong-Ho; Franke, Adrian A; Shu, Xiao-Ou; Li, Honglan; Ji, Butian; Cai, Qiuyin; Chai, Weiwen; Zheng, Wei (2011-06)
    Low circulating levels of coenzyme Q(10) (CoQ(10)) have been associated with increased cancer incidence and poor prognosis for a number of cancer types, while a recent prospective study observed a positive association for ...
  • Chai, Weiwen; Cooney, Robert V; Franke, Adrian A; Shvetsov, Yurii B; Caberto, Christian P; Wilkens, Lynne R; Le Marchand, Loïc; Henderson, Brian E; Kolonel, Laurence N; Goodman, Marc T (2010-09)
    Coenzyme Q10 (CoQ10) is a component of the mitochondrial electron transport chain and is considered an important cellular antioxidant. Decreased circulating CoQ10 levels have been reported in women with breast cancer, but ...
  • Chai, Weiwen; Cooney, Robert V; Franke, Adrian A; Caberto, Christian P; Wilkens, Lynne R; Le Marchand, Loïc; Goodman, Marc T; Henderson, Brian E; Kolonel, Laurence N (2011-04)
    Coenzyme Q10 (CoQ10) is considered to be a potential anticancer agent, but epidemiologic evidence regarding CoQ10 and prostate cancer risk is lacking. We examined the association of circulating CoQ10 levels with prostate ...

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