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Title: Validation of the human activity profile in the HIV-Positive population using indirect calorimetry 
Author: Barnett, Alexis T
Date: 2008
Abstract: Objective(s): To determine if the HAP is a valid measure of physical activity level for the HIV-Positive population. Design: Validation using VO2max as the "gold standard" to compare HAP scores resulting from the Maximal Activity Score (MAS) and the Adjusted Activity Score (AAS). Setting: Clinical laboratory Participants: Twenty-six HN-positive participants (23 male, 3 female; age 45.96±9.28 years) receiving HAART. Intervention: Participants completed the HAP and the exercise test on the same day. Maximal oxygen uptake was determined using standard indirect calorimetry techniques. Responses to the HAP resulted in two scores: the maximal activity score (MAS: maximal activity that is still being performed) and the adjusted activity score (AAS: MAS minus the number of activities that the subject can no longer perform). Correlations between AAS, MAS and VO2 max were generated. Main Outcome: MAS, AAS, and VO2max values. VO2max values were assessed using indirect Calorimetry. Results: Mean VO2max was 37.73 ± 6.95 ml O2kg-lmin-l. The mean MAS and AAS scores were 86.5 ± 7.6 and 75.7 ± 19.2, respectively. The VO2max was poorly correlated with MAS and AAS at p =0.31 and p =0.32, respectively. The poor correlations were likely due to the fact that the mean VO2max of the subjects in the present study exceeded 10 METS, the design limitations of the HAP. Conclusions: Based on the validation criteria used in the present study, the HAP is not a valid indicator of physical activity capacity for HIV -positive patients on HAART. Further study is needed to find a more accurate instrument to estimate physical activity capacity for this population.
Description: Thesis (M.S.)--University of Hawaii at Manoa, 2008. vii, 61 leaves, bound 29 cm
URI: http://hdl.handle.net/10125/20672
Rights: All UHM dissertations and theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission from the copyright owner.

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